Comparative efficacy of different chemotherapies for non-Hodgkin lymphoma: a network-meta analysis.

ABSTRACT: This network meta-analysis (NMA) was conducted to integrate different chemotherapeutic regimens for non-Hodgkin lymphoma (NHL) patients. Overall survival (OS) and complete remission (CR) were considered as main outcome indicators to evaluate the efficacy of NHL chemotherapies. OS and CR data were extracted from included studies and represented by hazard ratio and odds ratio separately. Network structure and forest plots were further included to visually present the relative efficacy among different regimens. A total of 14 qualified publications with 4,167 patients were included. In OS results, no significant difference was observed from the 1-year OS. For 2-year, 3-year and 5-year OS, patients treated by CNOP exhibited the least favorable results. Moreover, significant advantages of R-CHOP

SUBMITTER: Cai P 

PROVIDER: S-EPMC5710919 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature