Childhood victimization and inflammation in young adulthood: A genetically sensitive cohort study.

ABSTRACT:

Objective

Childhood victimization is an important risk factor for later immune-related disorders. Previous evidence has demonstrated that childhood victimization is associated with elevated levels of inflammation biomarkers measured decades after exposure. However, it is unclear whether this association is (1) already detectable in young people, (2) different in males and females, and (3) confounded by genetic liability to inflammation. Here we sought to address these questions.

Method

Participants were 2232 children followed from birth to age 18years as part of the Environmental Risk (E-Risk) Longitudinal Twin Study. Childhood victimization was measured prospectively from birth to age 12years. Inflammation was measured through C-reactive protein (CRP) levels in dried blood

SUBMITTER: Baldwin JR 

PROVIDER: S-EPMC5710993 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature