Small Vessel Disease and Dietary Salt Intake: Cross-Sectional Study and Systematic Review.

ABSTRACT:

Background

Higher dietary salt intake increases the risk of stroke and may increase white matter hyperintensity (WMH) volume. We hypothesized that a long-term higher salt intake may be associated with other features of small vessel disease (SVD).

Methods

We recruited consecutive patients with mild stroke presenting to the Lothian regional stroke service. We performed brain magnetic resonance imaging, obtained a basic dietary salt history, and measured the urinary sodium/creatinine ratio. We also carried out a systematic review to put the study in the context of other studies in the field.

Results

We recruited 250 patients, 112 with lacunar stroke and 138 with cortical stroke, with a median age of 67.5 years. After adjustment for risk factors, including age and hyperte

SUBMITTER: Makin SDJ 

PROVIDER: S-EPMC5711036 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature