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Geometric and dosimetric uncertainties in intracranial stereotatctic treatments for multiple nonisocentric lesions.


ABSTRACT: The purpose of this study was to determine the effects of geometric uncertainties of patient position on treatments of multiple nonisocentric intracranial lesions. The average distance between lesions in patients with multiple targets was determined by a retrospective survey of patients with multiple lesions. Retrospective patient imaging data from fractionated stereotactic patients were used to calculate interfractional and intrafractional patient position uncertainty. Three different immobilization devices were included in the positioning study. The interfractional and intrafractional patient positioning error data were used to calculate the geometric offset of a lesion located at varying distances from the mechanical isocenter for treatments of multiple lesions with a single arc, assumi

SUBMITTER: Winey B 

PROVIDER: S-EPMC5711043 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature