Assessment of Lungs for Transplant Recovered from Uncontrolled Donation after Circulatory Determination of Death Donors.

ABSTRACT:

Rationale

To address the lung donor shortage, we obtained institutional review board and US Food and Drug Administration approval to transplant lungs recovered from uncontrolled donation after circulatory determination of death donors (uDCDDs).

Objectives

To compare outcomes of recipients of lungs recovered from uDCDDs vs. brain-dead donors.

Methods

After consent and screening, lungs recovered from uDCDDs were assessed by 4 hours ex vivo lung perfusion (EVLP) and computed tomography (CT) scan.

Measurements and main results

Over the course of 29 months, 502 potential uDCDDs younger than 66 years were identified in a single county, with death declaration by emergency medical services and four emergency departments in this and two other countries. We determined re

SUBMITTER: Egan T 

PROVIDER: S-EPMC5711345 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature