Pramipexole Overdose Associated with Visual Hallucinations, Agitation and Myoclonus.

ABSTRACT:

Introduction

Pramipexole is a dopamine D₂ receptor agonist used to treat idiopathic Parkinson's disease and primary restless legs syndrome. There is limited information on pramipexole overdose.

Case report

A 59-year-old male ingested 3 mg pramipexole, 2250 mg venlafaxine, 360 mg mirtazapine, with suicidal intent. He presented alert, had normal vital observations and normal pupillary reflexes. He was mildly agitated, reported visual hallucinations and was given 5 mg diazepam. He had a mildly elevated lactate of 1.7 mmol/L, but otherwise normal laboratory investigations. Overnight, he remained agitated with visual hallucinations and developed myoclonus while awake. He had increasing difficulty passing urine on a background of mild chronic urinary retention. On revie

SUBMITTER: Cardon-Dunbar A 

PROVIDER: S-EPMC5711753 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature