Functional Components of Cognitive Impairment in Multiple Sclerosis: A Cross-Sectional Investigation.

ABSTRACT:

Background

Cognitive impairment is frequent and disabling in multiple sclerosis (MS). Changes in information processing speed constitute the most important cognitive deficit in MS. However, given the clinical and topographical variability of the disease, cognitive impairment may vary greatly and appear in other forms in addition to slower information processing speed. Our aim was to determine the frequency of cognitive impairment, the principal cognitive domains, and components involved in MS and to identify factors associated with presence of cognitive impairment in these patients in a large series of patients.

Methods

Cross-sectional study of 311 patients with MS [236 with relapsing-remitting MS (RRMS), 52 with secondary progressive MS (SPMS), and 23 with primary progressi

SUBMITTER: Matias-Guiu JA 

PROVIDER: S-EPMC5712315 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature