Severe Parechovirus 3 Infections in Young Infants-Kansas and Missouri, 2014.

ABSTRACT:

Background

Infection with parechovirus type 3 (PeV3) can cause severe neurologic and sepsis-like illness in young infants; clinical and epidemiologic descriptions have been limited. We aimed to characterize PeV3 illness and explore risk factors for acquisition in a cluster of neonatal cases at Children's Mercy Hospital in Kansas City, Missouri.

Methods

Cerebrospinal fluid specimens were obtained from infants aged <180 days who were hospitalized with sepsis-like illness or meningitis between June 1 and November 1, 2014. PeV-positive specimens were sequenced at the Centers for Disease Control and Prevention. We reviewed the medical and birth charts of the infants and performed face-to-face parent interviews. We analyzed characteristics according to infant age and intensive car

SUBMITTER: Midgley CM 

PROVIDER: S-EPMC5712449 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature