Dielectrophoretic Separation of Live and Dead Monocytes Using 3D Carbon-Electrodes.

ABSTRACT: Blood has been the most reliable body fluid commonly used for the diagnosis of diseases. Although there have been promising investigations for the development of novel lab-on-a-chip devices to utilize other body fluids such as urine and sweat samples in diagnosis, their stability remains a problem that limits the reliability and accuracy of readouts. Hence, accurate and quantitative separation and characterization of blood cells are still crucial. The first step in achieving high-resolution characteristics for specific cell subpopulations from the whole blood is the isolation of pure cell populations from a mixture of cell suspensions. Second, live cells need to be purified from dead cells; otherwise, dead cells might introduce biases in the measurements. In addition, the separation and ch

SUBMITTER: Yildizhan Y 

PROVIDER: S-EPMC5713632 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature