Four-dimensional tissue deformation reconstruction (4D TDR) validation using a real tissue phantom.

ABSTRACT: Calculation of four-dimensional (4D) dose distributions requires the remapping of dose calculated on each available binned phase of the 4D CT onto a reference phase for summation. Deformable image registration (DIR) is usually used for this task, but unfortunately almost always considers only endpoints rather than the whole motion path. A new algorithm, 4D tissue deformation reconstruction (4D TDR), that uses either CT projection data or all available 4D CT images to reconstruct 4D motion data, was developed. The purpose of this work is to verify the accuracy of the fit of this new algorithm using a realistic tissue phantom. A previously described fresh tissue phantom with implanted electromagnetic tracking (EMT) fiducials was used for this experiment. The phantom was animated using a sinu

SUBMITTER: Szegedi M 

PROVIDER: S-EPMC5713919 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature