Clinical Status of Adolescents with Perinatal HIV at Transfer to Adult Care in the UK/Ireland.

ABSTRACT:

Background

Increasing numbers of children infected perinatally with human immunodeficiency virus (HIV) are surviving to adolescence and transitioning to adult care, yet there are scarce data on their clinical status at transfer.

Methods

We analyzed prospective cohort data from the UK/Ireland national Collaborative HIV Pediatric Study (CHIPS). Clinical status at last pediatric clinic visit prior to transfer was described. Factors associated with higher CD4 cell count and viral load (VL) suppression<400 c/mL among patients on antiretroviral therapy (ART) at transfer were assessed using linear and logistic regression, respectively. Data were matched with the UK HIV Drug Resistance Database (UKHIVDRB) to assess cumulative resistance profiles at transfer.

Results

Of 1,907

SUBMITTER: Collins IJ 

PROVIDER: S-EPMC5714266 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature