Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children.

ABSTRACT:

Background

Long-term exposure to ambient air pollution can lead to adverse health effects in children; however, underlying biological mechanisms are not fully understood.

Objectives

We evaluated the effect of air pollution exposure during different time periods on mRNA expression as well as circulating levels of inflammatory cytokines in children.

Methods

We measured a panel of 10 inflammatory markers in peripheral blood samples from 670 8-y-old children in the Barn/Child, Allergy, Milieu, Stockholm, Epidemiology (BAMSE) birth cohort. Outdoor concentrations of nitrogen dioxide (NO₂) and particulate matter (PM) with aerodynamic diameter <10 μm (PM₁₀) from road traffic were estimated for residential, daycare, and school addresses using dispersion m

SUBMITTER: Gruzieva O 

PROVIDER: S-EPMC5714301 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature