Dataset Information

Site-level progression of periodontal disease during a follow-up period.

ABSTRACT: Periodontal disease is assessed and its progression is determined via observations on a site-by-site basis. Periodontal data are complex and structured in multiple levels; thus, applying a summary statistical approach (i.e., the mean) for site-level evaluations results in loss of information. Previous studies have shown the availability of mixed effects modeling. However, clinically beneficial information on the progression of periodontal disease during the follow-up period is not available. We conducted a multicenter prospective cohort study. Using mixed effects modeling, we analyzed 18,834 sites distributed on 3,139 teeth in 124 patients, and data were collected 5 times over a 24-month follow-up period. The change in the clinical attachment level (CAL) was used as the outcome variable. The CAL at baseline was an important determinant of the CAL changes, which varied widely according to the tooth surface. The salivary levels of periodontal pathogens, such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, were affected by CAL progression. "Linear"- and "burst"-type patterns of CAL progression occurred simultaneously within the same patient. More than half of the teeth that presented burst-type progression sites also presented linear-type progression sites, and most of the progressions were of the linear type. Maxillary premolars and anterior teeth tended to show burst-type progression. The parameters identified in this study may guide practitioners in determining the type and extent of treatment needed at the site and patient levels. In addition, these results show that prior hypotheses concerning "burst" and "linear" theories are not valid.

SUBMITTER: Nomura Y

PROVIDER: S-EPMC5714355 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Site-level progression of periodontal disease during a follow-up period.

Nomura Yoshiaki Y Morozumi Toshiya T Nakagawa Taneaki T Sugaya Tsutomu T Kawanami Masamitsu M Suzuki Fumihiko F Takahashi Keiso K Abe Yuzo Y Sato Soh S Makino-Oi Asako A Saito Atsushi A Takano Satomi S Minabe Masato M Nakayama Yohei Y Ogata Yorimasa Y Kobayashi Hiroaki H Izumi Yuichi Y Sugano Naoyuki N Ito Koichi K Sekino Satoshi S Numabe Yukihiro Y Fukaya Chie C Yoshinari Nobuo N Fukuda Mitsuo M Noguchi Toshihide T Kono Tomoo T Umeda Makoto M Fujise Osamu O Nishimura Fusanori F Yoshimura Atsutoshi A Hara Yoshitaka Y Nakamura Toshiaki T Noguchi Kazuyuki K Kakuta Erika E Hanada Nobuhiro N Takashiba Shogo S Amitani Yasuharu Y Yoshie Hiromasa H

PloS one 20171204 12

Periodontal disease is assessed and its progression is determined via observations on a site-by-site basis. Periodontal data are complex and structured in multiple levels; thus, applying a summary statistical approach (i.e., the mean) for site-level evaluations results in loss of information. Previous studies have shown the availability of mixed effects modeling. However, clinically beneficial information on the progression of periodontal disease during the follow-up period is not available. We ...[more]

PMID: 29206238

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Dataset Information

Site-level progression of periodontal disease during a follow-up period.

Publications

Site-level progression of periodontal disease during a follow-up period.

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