Distinguishing Among Modes of Convergent Adaptation Using Population Genomic Data.

ABSTRACT: Geographically separated populations can convergently adapt to the same selection pressure. Convergent evolution at the level of a gene may arise via three distinct modes. The selected alleles can (1) have multiple independent mutational origins, (2) be shared due to shared ancestral standing variation, or (3) spread throughout subpopulations via gene flow. We present a model-based, statistical approach that utilizes genomic data to detect cases of convergent adaptation at the genetic level, identify the loci involved and distinguish among these modes. To understand the impact of convergent positive selection on neutral diversity at linked loci, we make use of the fact that hitchhiking can be modeled as an increase in the variance in neutral allele frequencies around a selected site within

SUBMITTER: Lee KM 

PROVIDER: S-EPMC5714468 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature