Delirium Severity Post-Surgery and its Relationship with Long-Term Cognitive Decline in a Cohort of Patients without Dementia.

ABSTRACT:

Background

Delirium has been associated with more rapid cognitive decline. However, it is unknown whether increased delirium severity is associated with a higher rate of long-term cognitive decline.

Objective

To evaluate delirium severity and the presence and rate of cognitive decline over 36 months following surgery.

Methods

We examined patients from the Successful Aging after Elective Surgery Study, who were age ≥70 years undergoing major elective surgery (N = 560). Delirium severity was determined by the peak Confusion Assessment Method-Severity (CAM-S) score for each patient's hospitalization and grouped based on the sample distribution: scores of 0-2, 3-7, and 8-19. A neuropsychological composite, General Cognitive Performance (GCP), and proxy-reported Informant

SUBMITTER: Vasunilashorn SM 

PROVIDER: S-EPMC5714669 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature