Inference of Transcription Regulatory Network in Low Phytic Acid Soybean Seeds.

ABSTRACT: A dominant loss of function mutation in myo-inositol phosphate synthase (MIPS) gene and recessive loss of function mutations in two multidrug resistant protein type-ABC transporter genes not only reduce the seed phytic acid levels in soybean, but also affect the pathways associated with seed development, ultimately resulting in low emergence. To understand the regulatory mechanisms and identify key genes that intervene in the seed development process in low phytic acid crops, we performed computational inference of gene regulatory networks in low and normal phytic acid soybeans using a time course transcriptomic data and multiple network inference algorithms. We identified a set of putative candidate transcription factors and their regulatory interactions with genes that have

SUBMITTER: Redekar N 

PROVIDER: S-EPMC5714895 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature