Development and validation of a preoperative prognostic index independent of TNM stage in resected non-small cell lung cancer.

ABSTRACT:

Background

Previously reported prognostic tools for patients with resected non-small cell lung cancer (NSCLC) include factors found postoperatively, but not preoperatively. However, it would be important to predict patient prognosis before NSCLC resection. To suggest a novel preoperative prognostic tool, we evaluated the relationship of preoperative prognostic factors with the survival of patients with resected NSCLC.

Methods

We retrospectively reviewed the data of two independent cohorts of patients with completely resected NSCLC. To develop the prognostic index in one cohort, the overall survival (OS) was evaluated using the Cox proportional hazards model. We assessed the disease-free survival (DFS) and OS of three risk groups defined according to the prognostic index. The

SUBMITTER: Kumagai S 

PROVIDER: S-EPMC5715717 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature