Intact hemisphere and corpus callosum compensate for visuomotor functions after early visual cortex damage.

ABSTRACT: Unilateral damage to the primary visual cortex (V1) leads to clinical blindness in the opposite visual hemifield, yet nonconscious ability to transform unseen visual input into motor output can be retained, a condition known as "blindsight." Here we combined psychophysics, functional magnetic resonance imaging, and tractography to investigate the functional and structural properties that enable the developing brain to partly overcome the effects of early V1 lesion in one blindsight patient. Visual stimuli appeared in either the intact or blind hemifield and simple responses were given with either the left or right hand, thereby creating conditions where visual input and motor output involve the same or opposite hemisphere. When the V1-damaged hemisphere was challenged by incoming visual st

SUBMITTER: Celeghin A 

PROVIDER: S-EPMC5715784 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature