Pediatric cancer risk in association with birth defects: A systematic review.

ABSTRACT:

Background

Many epidemiological studies have examined associations between birth defects (BDs) and pediatric malignancy over the past several decades. Our objective was to conduct a systematic literature review of studies reporting on this association.

Methods

We used librarian-designed searches of the PubMed Medline and Embase databases to identify primary research articles on pediatric neoplasms and BDs. English language articles from PubMed and Embase up to 10/12/2015, and in PubMed up to 5/12/2017 following an updated search, were eligible for inclusion if they reported primary epidemiological research results on associations between BDs and pediatric malignancies. Two reviewers coded each article based on the title and abstract to identify eligible articles that were ab

SUBMITTER: Johnson KJ 

PROVIDER: S-EPMC5716403 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature