Long-term supplementation of decaffeinated green tea extract does not modify body weight or abdominal obesity in a randomized trial of men at high risk for prostate cancer.

ABSTRACT:

Background

Evidence continues to demonstrate the role of obesity in prostate carcinogenesis and prognosis, underscoring the need to identify and continue to evaluate the effective interventions to reduce obesity in populations at high risk. The aim of the study was to determine the effect of daily consumption of decaffeinated green tea catechins (GTC) formulation (Polyphenon E^® (PolyE)) for 1 year on biomarkers of obesity in men who are at high risk for prostate cancer.

Materials and methods

A randomized, double-blinded trial was conducted targeting 97 men diagnosed with HGPIN or ASAP. Subjects were randomized to receive GTC (PolyE) (n = 49) or placebo (n = 48) for 1 year. Anthropometric data were collected at baseline, 6 and 12 months and data analy

SUBMITTER: Kumar NB 

PROVIDER: S-EPMC5716795 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature