Signatures of positive selection and local adaptation to urbanization in white-footed mice (Peromyscus leucopus).

ABSTRACT: Urbanization significantly alters natural ecosystems and has accelerated globally. Urban wildlife populations are often highly fragmented by human infrastructure, and isolated populations may adapt in response to local urban pressures. However, relatively few studies have identified genomic signatures of adaptation in urban animals. We used a landscape genomic approach to examine signatures of selection in urban populations of white-footed mice (Peromyscus leucopus) in New York City. We analysed 154,770 SNPs identified from transcriptome data from 48 P. leucopus individuals from three urban and three rural populations and used outlier tests to identify evidence of urban adaptation. We accounted for demography by simulating a neutral SNP data set under an inferred demographic history as a n

SUBMITTER: Harris SE 

PROVIDER: S-EPMC5716853 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature