Achieved systolic blood pressure in older people: a systematic review and meta-analysis.

ABSTRACT:

Background

It remains unclear into which level the systolic blood pressure (SBP) should be lowered in order to provide the best cardiovascular protection among older people. Hypertension guidelines recommendation on attaining SBP levels <150 mmHg in this population is currently based on experts' opinion. To clarify this issue, we systematically reviewed and quantified available evidence on the impact of achieving different SBP levels <150 mmHg on various adverse outcomes in subjects aged ≥60 years old receiving antihypertensive drug treatment.

Methods

We searched 8 databases to identify randomized controlled trials (RCTs) and post-hoc analyses or subanalyses of RCTs reporting the effects of attaining different SBP levels <150 mmHg on the risk of stroke, acute myocardial infa

SUBMITTER: Moraes AAI 

PROVIDER: S-EPMC5717809 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature