Autoimmune-associated Congenital Heart Block: A New Insight in Fetal Life.

ABSTRACT:

Objective

Congenital heart block (CHB) is a rare but life-threatening disorder. More than half of CHB cases are associated with maternal autoimmune, which are termed as autoimmune-associated CHB. This review summarized the recent research findings in understanding autoimmune-associated CHB, discussed the current diagnostic approaches and management strategies, and summarized the problems and future directions for this disorder.

Data sources

We retrieved the articles published in English from the PubMed database up to January 2017, using the keywords including "Autoimmune-associated", "Autoimmune-mediated", and "Congenital heart block".

Study selection

Articles about autoimmune-associated CHB were obtained and reviewed.

Results

Observational studies consistently

SUBMITTER: Zhou KY 

PROVIDER: S-EPMC5717867 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature