Elevated ischemic stroke risk among women living with HIV infection.

ABSTRACT:

Objective

To determine if the greater risk of ischemic stroke observed in women living with HIV infection (WLWH) compared with HIV-uninfected women persists after accounting for both traditional and sex-specific stroke risk factors.

Methods

We performed an observational cohort study of WLWH (n = 1214) and demographics-matched HIV-uninfected women (n = 12 041) seen between 1996 and 2011 at two tertiary care hospitals in Boston. We used Cox proportional hazards regression analyses to model time to ischemic stroke, adjusting first for demographics and traditional stroke risk factors and then for sex-specific stroke risk factors, including menopause and estrogen use. We also constructed demographics-adjusted Cox models to identify HIV-related risk factors associated with ischemi

SUBMITTER: Chow FC 

PROVIDER: S-EPMC5718937 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature