Ontology highlight
ABSTRACT:
SUBMITTER: Henslee EA
PROVIDER: S-EPMC5719349 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Nature communications 20171207 1
Circadian rhythms organize many aspects of cell biology and physiology to a daily temporal program that depends on clock gene expression cycles in most mammalian cell types. However, circadian rhythms are also observed in isolated mammalian red blood cells (RBCs), which lack nuclei, suggesting the existence of post-translational cellular clock mechanisms in these cells. Here we show using electrophysiological and pharmacological approaches that human RBCs display circadian regulation of membrane ...[more]