Characterisation of a rare, reassortant human G10P[14] rotavirus strain detected in Honduras.

ABSTRACT:

Background

Although first detected in animals, the rare rotavirus strain G10P[14] has been sporadically detected in humans in Slovenia, Thailand, United Kingdom and Australia among other countries. Earlier studies suggest that the strains found in humans resulted from interspecies transmission and reassortment between human and bovine rotavirus strains.

Objectives

In this study, a G10P[14] rotavirus genotype detected in a human stool sample in Honduras during the 2010-2011 rotavirus season, from an unvaccinated 30-month old boy who reported at the hospital with severe diarrhea and vomiting, was characterised to determine the possible evolutionary origin of the rare strain.

Methods

For the sample detected as G10P[14], 10% suspension was prepared and used for RNA extrac

SUBMITTER: Quaye O 

PROVIDER: S-EPMC5719537 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature