The impact of virus infections on pneumonia mortality is complex in adults: a prospective multicentre observational study.

ABSTRACT:

Background

Various viruses are known to be associated with pneumonia. However, the impact of viral infections on adult pneumonia mortality remains unclear. This study aimed to clarify the effect of virus infection on pneumonia mortality among adults stratified by virus type and patient comorbidities.

Methods

This multicentre prospective study enrolled pneumonia patients aged ≥15 years from September 2011 to August 2014. Sputum samples were tested by in-house multiplex polymerase chain reaction assays to identify 13 respiratory viruses. Viral infection status and its effect on in-hospital mortality were examined by age group and comorbidity status.

Results

A total of 2617 patients were enrolled in the study and 77.8% was aged ≥65 years. 574 (21.9%) did not have comorbi

SUBMITTER: Katsurada N 

PROVIDER: S-EPMC5719746 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature