Association of salivary RANKL and osteoprotegerin levels with periodontal health.

ABSTRACT: The aim of this study is to determine the association of salivary levels of the bone remodelling regulators (RANKL) and osteoprotegerin (OPG) with periodontal clinical status. One-hundred fifty-eight participants selected from a pool of adult patients via systematic random sampling were included in this descriptive cross-sectional study carried out at the University of Nairobi Dental Hospital. About 5 ml of unstimulated whole saliva was collected from each participant followed by periodontal clinical examination. Salivary levels of RANKL and OPG were determined using human RANKL and OPG ELISA kits from R&D systems, UK. The mean salivary level of RANKL was 14.65pg/ml (+18.72 SD) with strong association to periodontal disease severity (F = 64.82, p < .001). Mean OPG levels was

SUBMITTER: Ochanji AA 

PROVIDER: S-EPMC5719813 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature