Salivary ammonia levels and Tannerella forsythia are associated with rheumatoid arthritis: A cross sectional study.

ABSTRACT: The aim of this paper is to evaluate the relationship of salivary ammonium levels and the presence of bacteria with rheumatoid arthritis (RA) clinical disease activity in a cross-sectional study of Mexican patients. From a periodontal and disease activity standpoint, 132 consecutive RA patients fulfilling clinical criteria were evaluated. Ammonia levels (including peptidyl arginine deiminase activity) were evaluated by colorimetric assay and the presence of Porphyromonas gingivalis, Tannerella forsythia, and Prevotella intermedia was evaluated by polymerase chain reaction (PCR) technique. After a multivariate analysis, adjusting for clinical and serological parameters, a significant association was only observed between severe periodontitis and probing depth with high

SUBMITTER: Martinez-Rivera JI 

PROVIDER: S-EPMC5719825 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature