Cyclic decomposition explains a photosynthetic down regulation for Chlamydomonas reinhardtii.

ABSTRACT: The regulation of metabolic networks has been shown to be distributed and shared through the action of metabolic cycles. Biochemical cycles play important roles in maintaining flux and substrate availability for multiple pathways to supply cellular energy and contribute to dynamic stability. By understanding the cyclic and acyclic flows of matter through a network, we are closer to understanding how complex dynamic systems distribute flux along interconnected pathways. In this work, we have applied a cycle decomposition algorithm to a genome-scale metabolic model of Chlamydomonas reinhardtii to analyse how acetate supply affects the distribution of fluxes that sustain cellular activity. We examined the role of metabolic cycles which explain the down regulation of photosynthesis that is obs

SUBMITTER: Chapman SP 

PROVIDER: S-EPMC5720477 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature