The obesity paradox and incident cardiovascular disease: A population-based study.

ABSTRACT:

Background

Prior work suggests that obesity may confer a survival advantage among persons with cardiovascular disease (CVD). This obesity "paradox" is frequently studied in the context of prevalent disease, a stage in the disease process when confounding from illness-related weight loss and selective survival are especially problematic. Our objective was to examine the association of obesity with mortality among persons with incident CVD, where biases are potentially reduced, and to compare these findings with those based on prevalent disease.

Methods

We used data from the Health and Retirement Study, an ongoing, nationally representative longitudinal survey of U.S. adults age 50 years and older initiated in 1992 and linked to Medicare claims. Cox proportional hazard models

SUBMITTER: Chang VW 

PROVIDER: S-EPMC5720539 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature