Association between memory impairment and brain metabolite concentrations in North Korean refugees with posttraumatic stress disorder.

ABSTRACT: Individuals with posttraumatic stress disorder (PTSD) had experiences of enormous psychological stress that can result in neurocognitive and neurochemical changes. To date, the causal relationship between them remains unclear. The present study is to investigate the association between neurocognitive characteristics and neural metabolite concentrations in North Korean refugees with PTSD. A total of 53 North Korean refugees with or without PTSD underwent neurocognitive function tests. For neural metabolite scanning, magnetic resonance spectroscopy of the hippocampus and anterior cingulate cortex (ACC) has been conducted. We assessed between-group differences in neurocognitive test scores and metabolite levels. Additionally, a multiple regression analysis was carried out to evaluate the asso

SUBMITTER: Shin JE 

PROVIDER: S-EPMC5720673 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature