Longer time to peak glucose during the oral glucose tolerance test increases cardiovascular risk score and diabetes prevalence.

ABSTRACT:

Introduction

The pattern of glucose levels during an oral glucose tolerance test (OGTT) may be useful for predicting diabetes or cardiovascular disease (CVD). Our aim was to determine whether the time to peak glucose during the OGTT is associated with CVD risk scores and diabetes.

Methods

Individuals with impaired fasting glucose (IFG) were enrolled in this observational study. Participants were grouped by the measured time to peak glucose (30, 60, 90 and 120 min) during the 75g OGTT. The primary outcome was 10-year CVD risk scores (using the Framingham risk score calculator). Secondary outcomes evaluated effect of time to peak glucose on prevalence of diabetes and indicators of glucose homeostasis.

Results

A total of 125 patients with IFG underwent OGTTs. Framingham

SUBMITTER: Lin YC 

PROVIDER: S-EPMC5720677 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature