The importance of thinking beyond the water-supply in cholera epidemics: A historical urban case-study.

ABSTRACT:

Background

Planning interventions to respond to cholera epidemics requires an understanding of the major transmission routes. Interrupting short-cycle (household, foodborne) transmission may require different approaches as compared long-cycle (environmentally-mediated/waterborne) transmission. However, differentiating the relative contribution of short- and long-cycle routes has remained difficult, and most cholera outbreak control efforts focus on interrupting long-cycle transmission. Here we use high-resolution epidemiological and municipal infrastructure data from a cholera outbreak in 1853 Copenhagen to explore the relative contribution of short- and long-cycle transmission routes during a major urban epidemic.

Methodology/principal findings

We fit a spatially explicit t

SUBMITTER: Phelps MD 

PROVIDER: S-EPMC5720805 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature