Natural history of aortic root aneurysms in Marfan syndrome.

ABSTRACT:

Background

Cardiovascular complications account for a significant proportion of the shortened lifespan of Marfan syndrome (MFS) patients, with aortic dissection being the most dreadful complication. The aortic root dilates initially in MFS patients, and given its important hemodynamic role, this can lead to aortic regurgitation and poses a substantial risk of aortic dissection. This study seeks to evaluate the natural history of aortic root aneurysms in MFS patients, with a focus on growth rates and correlation of root diameter with the risk of developing aortic complications.

Methods

Seventy-eight patients confirmed to have MFS and aortic root dilatation were retrospectively reviewed, and their aortic root diameters serially analyzed. Annual growth rate estimates and yearly

SUBMITTER: Saeyeldin A 

PROVIDER: S-EPMC5721101 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature