Definition, prevalence and predictive factors of benign multiple sclerosis.

ABSTRACT:

Background

Multiple sclerosis (MS) is characterized by a great inter-individual variability in disease course and severity. Some patients experience a rather mild course, controversially called 'benign MS' (BMS). The usefulness of this entity in clinical practice remains unclear.

Methods

We performed a literature search in PubMed, Web of Science and Cochrane Library databases from November 1980 to December 2015, using the following key words: benign multiple sclerosis, diagnosis, imaging, prognosis, predictive, natural history and predefined inclusion criteria.

Results

Our search yielded 26 publications. Most definitions were based on the Expanded Disease Status Scale (EDSS), which is heavily weighted towards physical disabili

SUBMITTER: Reynders T 

PROVIDER: S-EPMC5721547 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature