Intensity modulated radiation therapy and surgery for Management of Retroperitoneal Sarcomas: a single-institution experience.

ABSTRACT:

Background

Peri-operative radiation of retroperitoneal sarcomas (RPS) is an important component of multidisciplinary treatment. All retrospective series thus far included patients treated with older radiation therapy (RT) techniques including 2D and 3DRT. Intensity modulated radiation therapy (IMRT) allows for selective dose escalation while sparing adjacent organs. We therefore report the first series of patients with RPS treated solely with IMRT, surgery and chemotherapy. We hypothesized that IMRT would permit safe dose escalation and superior rates of local control (LC) in this high-risk patient population.

Methods

Thirty patients with RPS treated with curative intent between 2006 and 2015 were included in this retrospective study. RT was administered either pre- or post-

SUBMITTER: Cosper PF 

PROVIDER: S-EPMC5721605 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature