Comparison of two treatment approaches for prostate cancer: intensity-modulated radiation therapy combined with 125I seed-implant brachytherapy or 125I seed-implant brachytherapy alone.

ABSTRACT: The purpose of the present study was to assess the results of two different treatment approaches for clinically localized prostate cancer: intensity-modulated radiation therapy (IMRT) followed by 125I seed-implant brachytherapy and 125I seed-implant brachytherapy alone. We studied our 30 most recent consecutive patients. The sample population consisted of 15 cases treated with IMRT (50.4 Gy) followed by 125I seed-implant boost (95 Gy), and 15 cases treated with 125I seed implant only (144 Gy). We analyzed established dosimetric indices and various clinical parameters. In addition, we also evaluated and compared the acute urinary morbidities of the two treatment approaches, as assessed by the international prostate symptom score (IPSS). In our series, acute urinary morbidity was slightly in

SUBMITTER: Song Y 

PROVIDER: S-EPMC5721712 | biostudies-literature | 2008 Mar

REPOSITORIES: biostudies-literature