Comparative analyses of putative toxin gene homologs from an Old World viper, Daboia russelii.

ABSTRACT: Availability of snake genome sequences has opened up exciting areas of research on comparative genomics and gene diversity. One of the challenges in studying snake genomes is the acquisition of biological material from live animals, especially from the venomous ones, making the process cumbersome and time-consuming. Here, we report comparative sequence analyses of putative toxin gene homologs from Russell's viper (Daboia russelii) using whole-genome sequencing data obtained from shed skin. When compared with the major venom proteins in Russell's viper studied previously, we found 45-100% sequence similarity between the venom proteins and their putative homologs in the skin. Additionally, comparative analyses of 20 putative toxin gene family homologs provided evidence of unique seque

SUBMITTER: Krishnan NM 

PROVIDER: S-EPMC5721910 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature