Menopausal hormone therapy and pancreatic cancer risk in women: a population-based matched cohort study.

ABSTRACT:

Background

The role of menopausal hormone therapy (MHT) in the development of pancreatic cancer is inconclusive owing to small studies and lack of proper study design.

Methods

This population-based matched cohort study included all Swedish women who used systemic MHT between 1 July 2005 and 31 December 2012. For each user of MHT, three never-users of MHT were randomly selected, matched for childbirth, history of thromboembolic events, and previous hysterectomy, as well as for year of birth, diabetes, obesity, and smoking- or alcohol-related disorders. Multivariable conditional logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between MHT use and pancreatic cancer. The effect of MHT duration on pancreatic cancer

SUBMITTER: Sadr-Azodi O 

PROVIDER: S-EPMC5721980 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature