Dose modification factors for 192Ir high-dose-rate irradiation using Monte Carlo simulation.

ABSTRACT: A recently introduced brachytherapy system for partial breast irradiation, MammoSite, consists of a balloon applicator filled with contrast solution and a catheter for insertion of an 192Ir high-dose-rate (HDR) source. In using this system, the treatment dose is typically prescribed to be delivered 1 cm from the balloon's surface. Most treatment-planning systems currently in use for brachytherapy procedures use water-based dosimetry with no correction for heterogeneity. Therefore, these systems assume that full scatter exists regardless of the amount of tissue beyond the prescription line. This assumption might not be a reasonable one, especially when the tissue beyond the prescription line is thin. In such a case, the resulting limited scatter could cause an underdose to be delivered alon

SUBMITTER: Kassas B 

PROVIDER: S-EPMC5722431 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature