Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study: rationale and design.

ABSTRACT:

Background and aim

The association of HIV with coronary atherosclerosis has been established; however, the progression of coronary atherosclerosis over time among participants with HIV is not well known. The Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study is a large prospective multicenter study quantifying progression of coronary plaque assessed by serial coronary computed tomography angiography (CTA).

Patients and methods

HIV-infected and uninfected men who were enrolled in the Multicenter AIDS Cohort Study Cardiovascular Substudy were eligible to complete a follow-up contrast coronary CTA 3-6 years after baseline. We measured coronary plaque volume and characteristics (calcified and noncalcified plaque including fibrous, fibrous-fatty, and low

SUBMITTER: Nakanishi R 

PROVIDER: S-EPMC5722668 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature