Body-fat indicators and kidney function decline in older post-myocardial infarction patients: The Alpha Omega Cohort Study.

ABSTRACT: Background Obesity increases risk of hypertension and diabetes, the leading causes of end-stage renal disease. The effect of obesity on kidney function decline in stable post-myocardial infarction patients is poorly documented. This relation was investigated in a large cohort of older post-myocardial infarction patients. Design Data were analysed from 2410 post-myocardial infarction patients in the Alpha Omega Trial, aged 60-80 years receiving optimal pharmacotherapy treatment (79% men, 18% diabetes). Methods Cystatin C based estimated glomerular filtration rate (eGFR_cysC) was calculated at baseline and after 41 months, using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Obesity was defined as body mass index ≥ 30 kg/m² and high waist circu

SUBMITTER: Esmeijer K 

PROVIDER: S-EPMC5724586 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature