Novel systems for the application of isolated tensile, compressive, and shearing stimulation of distraction callus tissue.

ABSTRACT:

Background

Distraction osteogenesis is a procedure widely used for the correction of large bone defects. However, a high complication rate persists, likely due to insufficient stability during maturation. Numerical fracture healing models predict bone regeneration under different mechanical conditions allowing fixation stiffness optimization. However, most models apply a linear elastic material law inappropriate for the transient stresses/strains present during limb lengthening or segment transport. They are also often validated using in vivo osteotomy models lacking precise mechanical regulation due to the unavoidable stimulation of secondary interfragmentary motion during ambulation under finitely stiff fixation. Therefore, in order to create a robust numerical model of distracti

SUBMITTER: Meyers N 

PROVIDER: S-EPMC5724890 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature