Potassium measurements and risk of type 2 diabetes: a dose-response meta-analysis of prospective cohort studies.

ABSTRACT:

Objective

To clarify the relationship between serum, dietary, and urinary potassium and the risk of type 2 diabetes mellitus (T2DM).

Materials and methods

We searched PubMed and EMBASE through January 6, 2017 for studies reporting risk estimates on the association of potassium measurements and the risk of T2DM. The summary risk estimates were obtained through a random-effects model. Dose-response analysis was conducted.

Results

Eight studies involving 5,053 cases and 119,993 individuals were included. A trend toward significance was found in the highest versus lowest meta-analysis on serum potassium and T2DM risk (RR = 0.79; 95% CI 0.60-1.04); moreover, the RR per 1 mmol/L increase in serum potassium was 0.83 (95% CI 0.73-0.95). A non-significant association of dietar

SUBMITTER: Peng Y 

PROVIDER: S-EPMC5725047 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature