Regional lymph node involvement and outcomes in appendiceal neuroendocrine tumors: a SEER database analysis.

ABSTRACT:

Background

Appendiceal neuroendocrine neoplasms are most often diagnosed incidentally during appendectomy. The need for subsequent right hemicolectomy (RHC) is determined based on the risk of regional lymph node (LN) involvement. Tumor size has historically been used as an indicator of this risk, but controversy remains regarding its cut off. Furthermore, the impact of RHC on survival is unclear.

Methods

We used the SEER database to identify patients diagnosed with appendiceal neuroendocrine tumors.

Results

Of 1731 patients, 38.0% had well-differentiated neuroendocrine tumors (WDNETs), 60.8% had mixed histology tumors (MHTs), and 1.2% had poorly differentiated neuroendocrine carcinomas (PDNECs). In patients with WDNETs and MHTs who had adequate lymphadenectomy, higher

SUBMITTER: Mehrvarz Sarshekeh A 

PROVIDER: S-EPMC5725113 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature