Prediction of alcohol use disorder using personality disorder traits: a twin study.

ABSTRACT:

Background and aims

The DSM-IV personality disorders (PDs) are comorbid with alcohol use disorder (AUD) and with each other. It remains unclear which PD criteria are most likely to drive onset and recurrence of AUD and which are merely confounded with those criteria. We determine which individual PD criteria predict AUD and the degree of underlying genetic and/or environmental aetiology.

Design

A prospective observational twin study.

Setting

Norway 1999-2011.

Participants

A total of 2528 and 2275 Norwegian adult twins in waves 1 and 2 variable-selection analyses, and 2785 in biometric analyses.

Measurements

DSM-IV PDs and their 80 criteria were assessed using a structured personal interview, and AUD using the World Health Organization's Composite Interna

SUBMITTER: Rosenstrom T 

PROVIDER: S-EPMC5725242 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature