Brain gene expression signature on primate genomic sequence evolution.
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ABSTRACT:
SUBMITTER: Barbash S
PROVIDER: S-EPMC5725417 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
Brain gene expression signature on primate genomic sequence evolution.
Barbash Shahar S Sakmar Thomas P TP
Scientific reports 20171211 1
Considering the overwhelming changes that occurred during primate evolution in brain structure and function, one might expect corresponding changes at the molecular level. Surprisingly, a relatively constrained gene expression pattern is observed in brain compared with other tissues among primates, an observation that calls for reassessment of RNA expression influence on primate genome evolution. We built phylogenetic trees based on genomic sequences of functional genomic regions and tissue-spec ...[more]
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