Primary prevention implantable cardioverter defibrillator in patients with non-ischaemic cardiomyopathy: a meta-analysis of randomised controlled trials.

ABSTRACT:

Objectives

The objective of this meta-analysis of randomised controlled trials (RCTs) is to evaluate the role of primary prevention implantable cardioverter defibrillator (ICD) in patients with non-ischaemic cardiomyopathy (NICM).

Setting

A meta-analysis of RCTs performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines.

Data sources

The PubMed, MEDLINE, Embase and Cochrane Central Register of Controlled Trials databases were searched for relevant articles.

Participants

A total of 5 RCTs with 2573 patients with NICM were included.

Intervention

Primary prevention ICD, compared with medical therapy alone.

Primary and secondary outcome measures

All-cause mortality (primary outcome) and sudden cardiac deat

SUBMITTER: Barakat AF 

PROVIDER: S-EPMC5726098 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature