Practice patterns and outcomes associated with early sedation depth in mechanically ventilated patients: a systematic review protocol.

ABSTRACT:

Introduction

Mechanical ventilation is a commonly performed intervention in critically ill patients. Frequently, these patients experience deep sedation early in their clinical course. Emerging data suggest that the practice of early deep sedation may negatively impact patient outcomes. The purpose of this review is to assess the world's literature to describe and determine the impact of early deep sedation on the outcomes of mechanically ventilated patients.

Methods and analysis

Randomised controlled trials and non-randomised studies will be eligible for inclusion in this systematic review. With the assistance of a medical librarian, we will comprehensively search MEDLINE, Embase, Scopus, Cochrane Central Register of Controlled Trials, Database of Abstracts of Reviews and E

SUBMITTER: Stephens RJ 

PROVIDER: S-EPMC5726115 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature